Outline of ProMED-mail posts


meningococcal meningitis – 2 hockey players died – Colorado

Filed under: meningococcal meningitis — support @ 8:59 AM

[追加 2010-12-30 21:55]
ProMED-mail Archive Number 20101230.4590
Published Date 30-DEC-2010
Subject PRO/EDR> Meningitis, meningococcal – USA (03): (CO) fatal

Date: Wed 29 Dec 2010
From: Adrienne LeBailly [edited]

The bacteria involved in the Larimer County outbreak are Neisseria meningitidis, serogroup C, …

An additional case of meningococcal meningitis that occurred at the same time as the hockey league outbreak (June 2010) did not grow out Neisseria meningitidis, but was identified by CDC (using PCR testing) as meningococcal serogroup B.

Approximately 11 000 persons received free vaccinations in November and December 2010.

Although 6 of the northern Colorado outbreak cases had not been vaccinated for meningococcal disease, the 2 most recent cases in CSU students — one of which was fatal — had both received meningococcal conjugate vaccine in 2006.

[Mod. ML氏解説: Data (
see http://www.cdc.gov/vaccines/recs/acip/downloads/mtg-slides-oct10/02-5-mening-mcv4.pdf
) indicate protection wanes within 5 years after vaccination. …]

Adrienne LeBailly, MD, MPH
Director, Larimer County Department of Health and Environment
Colorado, USA

[追加 2010-12-25 17:09]
ProMED-mail Archive Number 20101224.4536
Published Date 24-DEC-2010
Subject PRO/EDR> Meningitis, meningococcal – USA (02): (CO) fatal
Date: Thu 23 Dec 2010
Source: TheDenverChannel.com [edited]
URL http://www.thedenverchannel.com/health/26260041/detail.html

米国 Northern Colorado コロラド州北部の invasive meningococcal disease 侵襲性髄膜炎疾患 患者計 8人。同一株(髄膜炎菌 血清型群 C)の感染により敗血症(ラリマー郡の死亡例 4人の死因)、髄膜炎など発症。 http://wp.me/pPrkZ-eG 地域発生した株の無症状保菌者は多い。ワクチン有効であるが効果は5年程度。Colorado State University CSU コロラド州立大学の学生に再接種勧奨。
Twitter http://twitter.com/TweetMedmail/status/18581019250659328

The most recent case [8人目] was a CSU student [コロラド州立大学の学生] who was hospitalized in early December 2010 with a meningococcal disease. He was released from Poudre Valley Hospital about a week later and is believed to be doing well at his parents’ home out of state.

The linked cases include illnesses that killed a Metro State College [student] [発端症例 太字は死亡患者] in April 2010; caused a disabling case of meningitis in a CSU student in May 2010; led to 3 fatal meningococcal cases among 3 Fort Collins hockey players in June 2010; caused a less severe case in a hockey player’s child in August 2010; and killed a CSU student in October 2010.
[死亡患者 計 5人
発端患者 デンバー郡デンバー市 Metropolitan State College of Denver の学生 1人死亡
フォート コリンズ市ホッケーリーグ選手 3人死亡
コロラド州立大学 学生 1人死亡

“The Colorado Department of Public Health and Environment’s lab has confirmed that the bacteria that caused the recent infection were Group C meningococcal bacteria (also called Neisseria meningitidis, serogroup C [髄膜炎菌 血清型群 C]).
In addition, special molecular “fingerprinting” tests (called PFGE [pulsed field gel electrophoresis] tests) allowed them to confirm 8 of these cases were caused by identical strains [全 8症例の原因菌は同一株].”

Four of the 8 cases reported in Larimer County since May 2010 have been fatal.

All the 4 fatal cases in Larimer County have been from meningococcal sepsis [ラリマー郡の死亡例 4患者の死因は髄膜菌性敗血症], rather than meningococcal meningitis.

ProMED-mail Archive Number 20100625.2115
Published Date 25-JUN-2010
Subject PRO/EDR> Meningitis, meningococcal – USA: (CO) fatal
Date: Wed 23 Jun 2010
Source: AOL News [edited]

[Mod. ML氏解説および記事:
遺伝子的に同一の髄膜炎菌 Neisseria meningitidis 株により髄膜炎を来たした 5人中 4人の発症場所 コロラド州ラリマー郡 Larimer フォート・コリンズ市 Fort Collins (州都デンバーの北 105 Km)は コロラド州立大学 Colorado State University (CSU) の本拠地。

3人は大人のホッケーリーグ Fort Collins Adult Hockey League の選手(2人死亡/保健当局 23 Jun 2010 発表)で、同市で2010年6月9日開催されたゲームに参加した。

N.S. 28歳男性、機械工学士、妻は妊娠 6か月。 (死亡日 ? 22 Jun 2010)
B.W. 29歳の父親 2010年6月14日死亡。妻は CSUで働いている。
W.J. 3人目 休暇をとっていたモンタナ州 Montana で入院。危篤状態。

W.J.氏の検査結果はフォート コリンズ市に届いていないが、菌株の遺伝子は同一のようである。

players at the end of a [9 Jun 2010] hockey game in Fort Collins removed their mouth guards [マウスガード], then shook hands, spreading the bacteria through saliva on their hands, …

Since meningitis is spread through contact with infected saliva or nasal fluids, it is also possible that this outbreak was transmitted through spitting [唾を吐く] during the game or sharing of water bottles [水筒の共用], …
[Mod. ML氏解説および記事:

同市の4人目の患者は同大学の学生で、2010年5月下旬 [戦没者追悼記念日 Memorial Dayの週末 29-31 May 2010] に発症し、デンバーに移送された。ホッケーの選手・試合とは無関係らしい。

5人目[発端者 死亡]は他の患者との疫学的な関連性は不明で、2010年4月 デンバー Denverで発症した。

The average incubation period for meningococcal meningitis is 4 days, ranging between 2 and 10 days

An outbreak of meningococcal disease in either an organization or community is defined as the occurrence of 3 or more confirmed or probable cases during a period of less than or equal to 3 months, resulting in a primary disease attack rate in the population at risk (such as, hockey team in the outbreak in the news release above) of at least 10 cases per 100 000 persons, which is about 10 times greater than the normal occurrence


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